The Indonesian Institute of Sciences (LIPI) and several medical associations conduct clinical trials on immunomodulators in herbal supplements to treat COVID-19 patients. Immunomodulators are substances that can affect the body’s immune system (strengthen or suppress the immune system, so it doesn’t overreact).
This clinical trial was conducted on 90 COVID-19 patients at
the Wisma Atlet Kemayoran COVID-19 Emergency Hospital, Jakarta. Supplement
testing is just one of the hundreds of scientists’ efforts to fight the
coronavirus that causes COVID-19. How is the process and progress of clinical
trials of this herbal supplement in Indonesia?
COVID-19 herbal supplement candidate
“This is not a drug that kills viruses in the body, but an
immunomodulator whose function is the same as a supplement as an immune system
enhancer to help fight viruses,” said Dr. Masteria Yunovilsa Putra to Hello
Sehat, Friday (7/8). Masteria is a doctor at the LIPI Biotechnology Research Center
as Coordinator of Clinical Test Activities for Immunomodulator Candidates.
When the body is attacked by a virus, the immune system or
immune system is the first to fight the virus. A sick body due to a virus
indicates that the resistance given by the body’s immune system has been lost.
This is when immunomodulators play a role in restoring the body’s immune
strength so that it can fight back against viral attacks.
The COVID-19 herbal immunomodulator is currently in
clinical trials, combines two finished products circulating in the
community. These immunomodulators have received marketing authorization from
the Food and Drug Supervisory Agency (BPOM) as standardized herbal medicines.
Masteria did not mention the distribution brand, but he
explained the herbal content of this COVID-19 immunomodulator candidate. First,
herbal supplements with the essential ingredients of Cordyceps militaris, a
mushroom plant with active compounds to overcome shortness of breath. Second,
the supplement comes from ginger rhizome, meniran, sambiloto, and sembung
leaves.
“Now, we want to claim it as an immunomodulator for COVID-19
supplements. That’s a special claim, so it must be tested,” said Masteria.
Herbal immunomodulator clinical trial in 90 Coronavirus infection patients
Patients who are test participants are COVID-19 patients
aged 18-50 years with mild symptoms and no comorbidities.
Of the total 90 participants, 72 were tested in early
August. Researchers said the entire series of clinical trials were completed on
Saturday (15/8).
Research on this COVID-19 immunomodulator candidate has been
conducted by the LIPI research team, Gadjah Mada University, and PT since early
March. Kalbe Farma Tbk.
Researchers conducted a scientific study of herbal
ingredients native to Indonesia which have active ingredients to boost the
immune system.
After determining and selecting two combinations of herbal
supplements, the research team chose the Wisma Athlete Emergency Hospital as
the test site. This is because the inclusion criteria of patients treated there
follow the target of the test.
In this clinical trial process, the research consisted of
the LIPI research team, the Association of Indonesian Traditional Medicine and
Herbal Medicine Development Doctors (PDPOTJI), the Indonesian Lung Doctors
Association (PDPI), the Research and Development Agency of the Ministry of
Health, and a team of doctors from the Emergency Hospital Handling COVID-19.
Kemayoran Athlete House.
“We hope that this immunomodulator will not only be used for
COVID-19 patients but can also be circulated in the community as an immune
enhancer and prevention of COVID-19,” said Masteria regarding her hopes for
this herbal supplement.
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source: https://hellosehat.com/infection/covid19/suplemen-herbal-covid-19/